A 23-year-old man suffered a stab wound and two other men were seriously injured during an altercation at Rockingham Street on Sunday morning.
Police and Emergency services were called to Cocoon nightclub at 3.55am following reports three people had been hurt.
One man was taken to hospital after being stabbed in the hand but was discharged shortly after.
The two other men are currently receiving treatment for upper-body puncture injuries described as serious but not life threatening.
South Yorkshire Police will be reviewing CCTV from the surrounding area and urge anyone with information call 101 quoting the incident number 184 of 17 February 2019.
Information can also be given to Crimestoppers anonymously on 0800 555111.